Mid-Town Historic District or Midtown Historic District may refer to:
(by US state) Midtown Historic District (Mobile, Alabama), listed on the National Register of Historic Places (NRHP) Midtown Historic District (Atlanta, Georgia), NRHP-listed Midtown Woodward Historic District, Detroit, Michigan, NRHP-listed Midtown Corinth Historic District, Corinth, Mississippi, NRHP-listed Mid-Town Historic District (Meridian, Mississippi), NRHP-listed Midtown Historic District (St. Louis, Missouri), NRHP-listed Mid-Town Historic District (Springfield, Missouri), NRHP-listed Mid-Town Historic District (Elizabeth, New Jersey), NRHP-listed Midtown Harrisburg Historic District, Harrisburg, Pennsylvania, NRHP-listed