McKeen is a surname. Notable people with the surname include:
Allyn McKeen (1905–1978), American football player and coach Angus McKeen (born 1969), Irish rugby union player Bob McKeen (1933–1999), American basketball player Charles McKeen (1885–1972), Canadian politician Erica McKeen, Canadian author H. Boyd McKeen (1835–1864), Union Army officer Jock McKeen (born 1946), Canadian physician John Elmer McKeen, American chief executive Joseph McKeen (1757–1807), American educator Nery McKeen (born 1957), Cuban middle-distance runner Nineveh S. McKeen (1837–1890), American soldier Philena McKeen (1822–1898), American educator Robert McKeen (1884–1974), New Zealand politician Stan McKeen (born 1982), Canadian rugby union player Stanley McKeen (1897–1966), Canadian politician William McKeen (born 1954), American academic William R. McKeen Jr. (1869–1946), American inventor and businessman
See also McKean (surname) McKeon