Negroni is an Italian/Corsican surname. Notable people with the surname include:

Andrea Negroni (1710–1789), Italian Cardinal Baldassarre Negroni (1877–1948), Italian film director and screenwriter Christine Negroni (born 1956), American aviation and travel writer Daniele Negroni (born 1995), Italian singer and runner-up on Deutschland sucht den Superstar (season 9) Giovanni Francesco Negroni (1629–1713), Italian Cardinal Héctor Andrés Negroni (born 1938), American Air Force officer, historian and aerospace senior executive Jean Négroni (1920–2005) French actor Joe Negroni (1940–1978), American singer of Puerto Rican descent Luca Negroni (born 1964), Italian ski mountaineer María Negroni (born 1951), Argentinian poet, essayist, novelist and translator General Pascal Olivier Count de Negroni (1829–1913), led the charge of Cuirassiers in the Battle of Reichshoffen during the Franco-Prussian War of 1870 Pietro Negroni (c. 1505–1565), Italian painter of the Renaissance period

Other Negroni, cocktail credited to various people by this name

See also Neroni, also an Italian surname