In organic chemistry the Hoch-Campbell ethylenimine synthesis is a method for constructing ethyleneimines from oximes. The oxime is treated with Grignard reagents:(a), Hoch, Compt. rend., 196, 1865 (1934); (b), ibid., 203, 799 (1936); (c), ibid., 204, 358 (1937).
The above product is called 3-methyl-2,2-diphenylaziridine [7764-13-8]. Campbell describes a compound that is called 2-amino-1,1-diphenylpropan-1-ol [57728-35-5]. This is an open-chain analog of pipradrol. 99% of the theoretical yield can be achieved by Grignard addition of two equivalents of phenylmagnesium bromide to alanine ethyl ester. This compound has remarkable similarity to Diphepanol & Hexapradol.
N.B. Joseph Hoch was the first chemist to invent diphenylacetonitrile. References