Bartolome is a Tagalog surname and may refer to:
Alex Bartolome (1958–2000), Filipino rapist and last person executed in the Philippines Donnalyn Bartolome (1994), Filipina internet personality, vlogger, singer, songwriter and rapper Heber Bartolome (1948–2021), Filipino folk and rock singer, songwriter, composer, poet, guitarist and bandurria Vic Bartolome (1948), American former professional basketball player