Labeo is an ancient Roman cognomen derived from the word labea (English: lip), originally referring to a person with thick or prominent lips.

Labeo may refer to:

Attius Labeo, 1st century AD Roman writer whose translations of the Iliad and the Odyssey were derided Claudius Labeo, Batavian military leader who fought for Rome in the Batavian rebellion (69–70 AD) Cornelius Labeo, 3rd century AD(?) Roman theologian and antiquarian Gaius Atinius Labeo (praetor 195 BC), tribune of the plebs in 196 BC Gaius Atinius Labeo (praetor 190 BC) Marcus Antistius Labeo (died 10 or 11 AD), Roman jurist, son of Pacuvius Labeo Pacuvius Labeo (died 42 BC), Roman jurist and assassin of Julius Caesar Quintus Fabius Labeo (), Roman quaestor, praetor, consul and pontiff