HLA-B (alpha)-β2MG with bound peptide major histocompatibility complex (human), class I, B14 Alleles B*1401, 1402 . . Structure (See HLA-B) Shared data Locus chr.6 6p21.31 HLA-B14 (B14) is a HLA-B serotype. The serotype identifies the B*45 gene-allele protein products of HLA-B.
B14 is a broad antigen composed to two, B64 and B65, split antigens. In the case of B14 the recognition of the broad antigen is more useful than split antigen recognition because of the relatively poor discrimination of the split antigens (see Table below).
Serotype + B14, B64, B65 serotype recognition of some HLA B*14 allele-group gene products B*14 B14 B64 B65 Sample allele % % % size (N) 1401 72 10 10 1006 1402 71 2 25 2244 1403 50 35 40 Alleles link-out to IMGT/HLA Databease at EBI
HLA-B64 This serotype does not have good recognition of any of the alleles, relatively speaking recognizes B*1401 better.
HLA-B65 This serotype recognizes B*1402 and B*1403 but less so than B14 and to a minor degree it recognized B*1401.
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