KSCB may refer to:
KSCB (AM), a radio station (1270 AM) licensed to Liberal, Kansas, United States KSCB-FM, a radio station (107.5 FM) licensed to Liberal, Kansas, United States K53EG, a television station (channel 53) licensed to Sioux Falls, South Dakota, United States, also known as KSCB-TV Scribner State Airport (ICAO code KSCB)