Four Souls may refer to:
Four Souls (novel), a 2004 novel by Louise Erdrich Lenny McBrowne and the Four Souls, an American jazz group Four Souls, a 2002 ballet by Francesco Libetta "Four Souls", a chapter of the manga series Saint Seiya: The Lost Canvas
See also The Binding of Isaac: Four Souls, a card game Jewel of Four Souls, a fictional object in the manga series Inuyasha