High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene.
Interactions
The FcgRI binds the Fc portion of IgG and causes activation of the host cell via an intercellular ITAM motif.The function of Fcγ receptors in dendritic cells and macrophages Martin Guilliams Pierre Bruhns Yvan Saeys Hamida Hammad and Bart N. Lambrecht FEBRUARY 2014 | VOLUME 14 Nature Reviews Immunology
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