The House of Tusishvili (; archaically known as Tusisshvili, ) was a Georgian princely family, known in the eastern province of Kakheti since 1469.
History The Tusishvili branched off the House of Zedginidze. They had their estates at Akhmeta and Gagma-Mkhari on the left bank of the Alazani. After Russian annexation of Georgia in 1801, the family was incorporated among the Russian princely houses in 1850.Toumanoff, Cyril (1963), Studies in Christian Caucasian History, p. 271. Georgetown University Press.Bagrationi, Ioane (1768-1830). Tusis-shvili (Princes of Kakheti). The Brief Description of the Georgian Noble Houses. Retrieved on December 19, 2007.
A notable member of this family was the 18th-century churchman Saba Tusishvili, Metropolitan Bishop of Ninotsminda (1744–88), and a close associate of King Erekle II.
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