Konstantinou or Constantinou or Kostandinou () is a Greek surname, the genitive form of "Constantine". It is a common name in Greece and Cyprus. Notable people with surname Konstantinou include

Alex Konstantinou (born 1992), Cypriot footballer Andreas Constantinou (born 1980), Cypriot footballer Chris Constantinou, English musician Clay Constantinou (born 1951), American diplomat Fivos Constantinou (born 1981), Cypriot distance runner Giorgos Konstantinou (born 1934), Greek actor and director Konstantinos Konstantinou (cyclist), Greek cyclist Martha Constantinou, Cypriot-American physicist Michalis Konstantinou (born 1978), Cypriot footballer Nik Constantinou (born 1999), Australian-American football player Stavros Konstantinou (born 1984), Cypriot singer Tasos Konstantinou (1951–2019), Cypriot footballer, known as "Tasos" Vasilis Konstantinou (born 1947), Greek footballer

See also Konstantinou kai Elenis, Greek sitcom