Lipase member H is an enzyme that in humans is encoded by the LIPH gene. Also sometimes called Phosphatidic acid-specific PLA1β, this enzyme functions as a phospholipase that specifically acts on phosphatidic acid, producing the signaling molecule 2-acyl lysophosphatidic acid (LPA). LPA is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility.
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