Flatow is a surname. Notable people with the surname include:
Alfred Flatow (1869–1942), German gymnast Alisa Flatow (1974–1995), American student and terrorism victim Curth Flatow (1920–2011), German dramatist and screenwriter Evan Flatow (born 1956), American orthopaedic surgeon Fred Flatow (born 1937), Australian-German chess master Gustav Flatow (1875–1945), German gymnast Ira Flatow (born 1949), radio and television journalist, NPR Max Flatow (1915–2003), American architect Stephen Flatow (born 1948) American lawyer and father of terrorism victim Alisa Flatow