Rho GTPase-activating protein 33 is a protein that in humans is encoded by the ARHGAP33 gene (previously SNX26). Predictions suggest that it may be involved in insulin signaling and glucose transport, potentially as a downstream effector of RHOQ.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.
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