PKD2L1

Polycystic kidney disease 2-like 1 protein also known as transient receptor potential polycystic 3 (TRPP3) is a protein that in humans is encoded by the PKD2L1 gene.

Function

PKD2L1 is a member of the polycystin protein family. PKD2L1 contains multiple transmembrane domains, and cytoplasmic N- and C-termini. PKD2L1 may be an integral membrane protein involved in cell-cell/matrix interactions. PKD2L1 functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.

Interactions

PKD2L1 has been shown to interact with TNNI3.

See also TRPP

References

Further reading