In renal physiology, renal chloride reabsorption refers to the process by which the kidneys, having filtered out waste products from the blood to be excreted as urine, re-absorb chloride ions () from the waste.
Overview table + Characteristics of Cl− reabsorptionCharacteristicProximal tubuleLoop of HenleDistal convoluted tubuleCollecting duct system S1 S2 S3 descending limb thin ascending limb thick ascending limb connecting tubule initial collecting tubule cortical collecting ducts medullary collecting ductsreabsorption (%) reabsorption (mmoles/day) concentration (mM) 115 135 electrical driving force (mV) −3 Page 777 +3 +15 −5 to +5 −40 chemical driving force (mV) electrochemical driving force (mV) (positive) Page 779 apical transport proteins (passively) Cl-formate exchanger Cl-oxalate exchanger Cl−-OH− exchanger Na-K-2Cl cotransporter Na-Cl cotransporter principal cells: paracellularily basolateral transport proteins chloride channels Cl-K cotransporter Page 780 Cl−/HCO3− exchanger chloride channels chloride channels chloride channels β intercalated cells: Cl−HCO3− exchanger other reabsorption features
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