James Chalmers may refer to:
James Chalmers (loyalist) (c. 1730–1806), Scottish-born Loyalist officer from Maryland in the American Revolutionary War James Chalmers (inventor) (1782–1853), Scottish inventor of the adhesive postage stamp James Ronald Chalmers (1831–1898), American politician James Chalmers (missionary) (1841–1901), Scottish-born missionary to New Guinea James Chalmers (actor) (born 1974), British actor James Chalmers (footballer) (1877–?)
See also Jim Chalmers (disambiguation) James Chalmers McRuer (1890–1985), Canadian lawyer and author