Carboxylesterase, type B is a family of evolutionarily related proteins that belongs to the superfamily of proteins with the Alpha/beta hydrolase fold.
Higher eukaryotes have many distinct esterases. The different types include those that act on carboxylic esters (). Carboxyl-esterases have been classified into three categories (A, B and C) on the basis of differential patterns of inhibition by organophosphates. The sequence of a number of type-B carboxylesterases indicates that the majority are evolutionarily related. As is the case for lipases and serine proteases, the catalytic apparatus of esterases involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.
Subfamilies Neuroligin Cholinesterase
Examples
Human genes that encode proteins containing the carboxylesterase domain include:
ACHE ARACHE BCHE CEL CES1 CES2 CES3 CES4 CES7 CES8 NLGN1 NLGN2 NLGN3 NLGN4X NLGN4Y TG
See also Carboxylesterase
References
External links Carboxylesterases type-B in PROSITE