Beta-pyrazolylalanine synthase () is an enzyme that catalyzes the chemical reaction
It was first characterised from Leucaena leucocephala and transfers the 2-amino-2-carboxyethyl group from its substrate, the amino acid O-acetylserine, to pyrazole, giving β-pyrazolyl-L-alanine. Acetic acid () is a byproduct. The enzyme is also found in Citrullus vulgaris (watermelon) and, unlike some other cysteine synthase enzymes which use O-acetylserine, in this species is specific for pyrazole.
This enzyme is a transferase, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase. Other names in common use include beta-(1-pyrazolyl)alanine synthase, beta-pyrazolealanine synthase, beta-pyrazolylalanine synthase (acetylserine), O3-acetyl-L-serine acetate-lyase (adding pyrazole), BPA-synthase, pyrazolealanine synthase, pyrazolylalaninase, and 3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase.
References