Succinylglutamate desuccinylase () is an enzyme characterised from the bacterium Pseudomonas cepacia that catalyzes the hydrolysis of N(2)-succinyl-L-glutamic acid to succinic acid and L-glutamic acid:
This is the final step in the catabolism of the amino acid arginine, which begins with arginine N-succinyltransferase.
This enzyme is a hydrolase, one acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-succinyl-L-glutamate amidohydrolase. Other names in use include N2-succinylglutamate desuccinylase, SGDS, and AstE (the gene).
References