Mandelamide amidase () is an enzyme characterised from Alcaligenes faecalis that hydrolyses the (R) enantiomer of mandelamide to (R)-mandelic acid and ammonia:
This enzyme is a hydrolase, one acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.
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