3-deoxy-manno-octulosonate-8-phosphatase (EC 3.1.3.45) catalyzes the reaction
The enzyme characterised from Escherichia coli uses water to hydrolyse the phosphate ester, 3-deoxy-α-D-manno-2-octulosonic acid 8-phosphate to the corresponding sugar, with orthophosphate (Pi) as byproduct. It is specific for its substrate and is part of the pathway to nucleoside sugars.
The enzyme is an hydrolase, specifically those acting on phosphoric monoester bonds. The systematic name is 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase.
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