Neuropeptide Y receptor type 1

Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene.

Selective ligands

Agonists Neuropeptide Y (endogenous agonist, non subtype selective) Peptide YY

Antagonists Peptide BVD-10 (selective NPY1 antagonist, CAS# 262418-00-8) GR-231,118 (mixed NPY1 antagonist / NPY4 agonist, CAS# 158859-98-4)

Non-peptide BIBO-3304 (CAS# 191868-14-1) BIBP-3226 (CAS# 159013-54-4) PD-160,170 (CAS# 181468-88-2)

Available Structures

5ZBH (Neuropeptide Y1 bound to antagonist BMS-193835) 5ZBQ (Neuropeptide Y1 bound to antagonist UR-MK299)

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