Spohr is a German surname. Notable people with the surname include:

Arnold Spohr (1923–2010), Canadian ballet dancer, choreographer, and artistic director of German descent Barbara Spohr (1955–1987), Canadian photographer Eduardo Spohr (born 1976), Brazilian fantasy and science fiction writer Louis Spohr (1784–1859), German composer, violinist, and conductor Max Spohr (1850–1905), German bookseller and publisher