IU may refer to:
Businesses and organizations
Sport Indiana Hoosiers, the athletic program of Indiana University Bloomington, often called (technically incorrectly) "IU" Islamabad United, a cricket team franchise in Pakistan Super League
Universities Ilam University, a public university in Ilam, Iran Indiana University, a multi-campus public university system in the state of Indiana, United States Indiana University Bloomington, the system's flagship campus and often conflated with the system Islamic University, Bangladesh Ho Chi Minh City International University, a member institution of Vietnam Vietnam National University in Ho Chi Minh city Independence University International University, Cambodia, a private higher education institution in Phnom Penh, Cambodia IU International University of Applied Sciences, Erfurt, Germany Isra University, Hyderabad, Sindh, Pakistan Istanbul University Ittihad University, Ras Al Khaimah, United Arab Emirates
Other organizations The IU, a Georgist political organization in London Intermediate Unit, a regional educational service agency in Pennsylvania Izquierda Unida ("United Left" in Spanish, political party) Izquierda Unida (Argentina) Izquierda Unida (Spain) Super Air Jet, IATA Code IU, an Indonesian airline
Language Intonational unit, a segment of speech Inuktitut language (ISO 639 alpha-2)
Science, technology, and mathematics Iu interface, in the RANAP telecommunications protocol Instruction unit, the part of a computer CPU that manages instruction fetch and instruction issue Saturn V instrument unit, a guidance system for the Saturn V rocket International unit, a unit for biological activity used in pharmacology Inter-universal Teichmüller theory, a mathematical theory by Shinichi Mochizuki
Arts and entertainment IU (entertainer) (born 1993), South Korean singer and actress I U (EP), a 2011 Japanese compilation album by IU