In enzymology, a phosphonopyruvate hydrolase () is an enzyme that catalyzes the chemical reaction
3-phosphonopyruvate + H2O pyruvate + phosphate
Thus, the two substrates of this enzyme are 3-phosphonopyruvate and H2O, whereas its two products are pyruvate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on carbon-phosphorus bonds. The systematic name of this enzyme class is '''. This enzyme is also called PPH'''.
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