Mencía is a feminine given name of Spanish origin, as well as a surname. It may refer to:

People Aída Mencía Ripley, Dominican scientist Mencía Calderón (1514–1564), Spanish noble lady and expeditionary woman Mencía López de Haro (1215–1270), Castilian noblewoman, Queen consort of Portugal Mencía de Mendoza (1508–1554), Dutch culture patron Carlos Mencía (b. 1967), American comedian of Honduran origin María Mencía, Spanish artist and researcher

Other uses Mencía (grape), grape variety from Spain Doña Mencía, Córdoba, Spain Mind of Mencia, TV show Epicopeia mencia, moth species