Trans-epoxysuccinate hydrolase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Pseudomonas putida hydrolyses both optical isomers of trans-2,3-epoxysuccinic acid to mesotartaric acid. The structure and mechanism of the enzyme from Pseudomonas koreensis has been studied as a means of producing mesotrtaric acid.
This enzyme is a hydrolase, specifically one acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is trans-2,3-epoxysuccinate hydrolase. Other names in common use include trans-epoxysuccinate hydratase, and tartrate epoxydase.
References