3-phenylpropanoate dioxygenase () is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are phenylpropanoic acid, reduced nicotinamide adenine dinucleotide (NADH), oxygen, and a proton. Its products are the cis-diol, 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]propanoic acid, and oxidised NAD+.
This enzyme is an oxidoreductase that uses molecular oxygen as oxidant and incorporates both its atoms into the starting material. The systematic name of this enzyme class is 3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating). Other names in common use include HcaA1A2CD, Hca dioxygenase, and 3-phenylpropionate dioxygenase. It can catalyse the same reaction in related compounds, for example cinnamic acid.
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