Iodophenol O-methyltransferase () is an enzyme that catalyzes the chemical reaction
This is a methylation reaction in which 2-iodophenol is converted to 2-iodoanisole. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which loses its methyl group and becomes S-adenosyl-L-homocysteine (SAH). Other iodophenols are also methylated, with the highest activity being found with 4-hydroxy-3,5-diiodobenzoic acid (ioxynic acid).
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:2-iodophenol O-methyltransferase.
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