8-hydroxyquercetin 8-O-methyltransferase () is an enzyme that catalyzes the chemical reaction
This is a methylation reaction in which the flavonol, gossypetin, is converted to the O-methylated flavonoid corniculatusin. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The product takes its name from the plant Lotus corniculatus in which it is found.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3,5,7,8,3',4'-hexahydroxyflavone 8-O-methyltransferase. Other names in common use include flavonol 8-O-methyltransferase, flavonol 8-methyltransferase, S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone, 8-O-methyltransferase, and 8-hydroxyquercitin 8-O-methyltransferase [mis-spelt].
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