Dioxaphetyl butyrate (INN; trade names Amidalgon, Spasmoxal) is an opioid analgesic which is a diphenylacetic acid derivative, related to other open-chain opioid drugs such as dextropropoxyphene, levacetylmethadol (LAAM), lefetamine and dimenoxadol.

It produces similar effects to other opioids, including dependence, euphoria, analgesia, sedation, constipation, dizziness and nausea.

Legal status

Dioxaphetyl butyrate is listed as an internationally controlled opioid under Schedule I of the 1961 Single Convention on Narcotic Drugs.[ref]

In Australia, the Office of Drug Control lists it as a narcotic requiring import and export licensing and permits.

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9621 and a 2013 annual aggregate manufacturing quota of zero.

Chemistry

Dioxaphetyl butyrate has the molecular formula C22H27NO3 and a molecular weight of approximately 353.45 g/mol. Its IUPAC name is ethyl 4-(morpholin-4-yl)-2,2-diphenylbutanoate. It is also listed under the names Amidalgon and Spasmoxal. References