Co-amilozide (BAN) is a non-proprietary combination of amiloride and hydrochlorothiazide. Co-amilozide is used in the treatment of hypertension and congestive heart failure with the tendency of the thiazide to cause low potassium levels (hypokalaemia) offset by the potassium-sparing effects of amiloride.
Formulation Two strengths of co-amilozide are currently available in the UK:British National Formulary 54 September 2007 2.5 mg amiloride and 25 mg hydrochlorothiazide, BAN of Co-amilozide 2.5/25 (brand name Moduret 25) 5 mg amiloride and 50 mg hydrochlorothiazide, BAN of Co-amilozide 5/50 (brand name Moduretic)
In North America: Moduretic (U.S., Canada) Moduretic 5-50 (U.S., Canada) Novamilor (Canada)
Side effects The most common side effect is headache (about 8% of people taking it) and nausea, loss of appetite, weakness, rash and dizziness (each about 3%).
Common side effects (1/10 - 1/100) include:the Swedish official drug catalog > Normorix Retrieved on Mars 30, 2010 General: weakness, fatigue, loss of appetite, headache, dizziness. Circulatory system: arrhythmia. Gastrointestinal: nausea, diarrhea, abdominal pain. Skin: exanthema, itching. Respiratory system: shortness of breath, cough. Metabolic: elevated blood sugar in diabetic patients, elevated uric acid levels in the blood. Musculoskeletal: pain in the limbs.
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