The Apelin Receptor is a G protein-coupled receptor which in humans is encoded by the gene APLNR (and also known as APJ). The structure of APLNR was resolved in 2017.
Ligands Agonists APLNR possesses two endogenous agonist ligands: APELIN ELABELA. Synthetic agonists include; Azelaprag (AMG 986, BGE-105) AM-8123 BMS-986224 CMF-019
Antagonists ML221
References
Further reading
External links