In enzymology, 2-oxoadipate reductase () is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are (R)-2-hydroxyadipic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 2-oxoadipic acid, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-hydroxyadipate:NAD+ 2-oxidoreductase. Other names in common use include 2-ketoadipate reductase, alpha-ketoadipate reductase, and 2-ketoadipate reductase.
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