LACA may refer to:
Places Los Angeles, California, the second most populous city in the US Latin America and Central America, a designation used by American businesses doing business globally
People Alexandre Lacazette (born 1991), nickname for the French footballer who plays for Arsenal. Ivan Laća (born 2003), Croatian professional footballer José María Laca (1898–1977), Spanish footballer
Other uses lacA, a structural gene in the lac operon