Pruno is an alcoholic beverage made from apples and/or oranges.

Pruno may also refer to:

Places France Pruno, Haute-Corse, a commune on Corsica

Italy Pruno (Cilento), a rural village in the comunes of Valle dell'Angelo and Laurino, and a big rural area in the middle of Cilento (Province of Salerno, Campania) Pruno (Stazzema), a hamlet (frazione) in the comune of Stazzema (Province of Lucca, Tuscany)

Biology Prunoideae, a subfamily of plants belonging to the family of Rosaceae Prunus, a genus of plants belonging to the family of Rosaceae

Other "Pruno", a Stone Temple Pilots song from the album No. 4