Deschutes River is a major tributary of the Columbia River in central Oregon, U.S.
Deschutes River (; Falls River) may also refer to: Little Deschutes River, a tributary of the Deschutes River in Oregon Deschutes River (Washington) River De Chute in Maine Rivière des Chutes (Batiscan River tributary), a river in Mauricie, Quebec, Canada
See also Deschutes (disambiguation) Falls River (disambiguation)