Mizolastine (Tradename: Mizollen) is a once-daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting. It does not prevent the actual release of histamine from mast cells, it only prevents histamine from binding to receptors. Side effects can include dry mouth and throat.

In an animal study, the antihistamine activity of Mizolastine was found to be similar to that of cetrizine and 7-fold more potent relative to loratadine.

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