Uziel or Uzziel () is documented as a Jewish family name in early 15th century Spain.
Notable people with this surname include:
Ben-Zion Meir Hai Uziel Isaac Uziel Jacob Uziel Joseph Uziel Judah Uziel Oren Uziel Samuel Uziel Yonatan Uziel David Uziel
See also (the father of) Jonathan ben Uzziel Hayyim ben Abraham Uziel Samuel ben Joseph Uziel Uziel Gal, designer of the Uzi submachine gun Uzi Uziel (angel)