Sanguinetti is an Italian surname. Notable people with the surname include:
Alessandra Sanguinetti (born 1968), American photographer Carlos Sanguinetti (born 1961), Argentine sailor Carmen Sanguinetti (born 1977), Uruguayan politician Davide Sanguinetti (born 1972), Italian tennis player Evelyn Sanguinetti (born 1970), American politician Frank Sanguinetti (1886–1973), Australian football player Frederick Sanguinetti (1847–1906), British colonial administrator Gianfranco Sanguinetti (1948–2025), Italian writer Giorgio Sanguinetti, Italian musicologist Giovanni Sanguinetti (born 2000), Italian volleyball player Guillermo Sanguinetti (born 1966), Uruguayan football player Javier Sanguinetti (born 1971), Argentine football player Jorge Sanguinetti (1934–2017), Uruguayan politician Julio María Sanguinetti (born 1936), Uruguayan politician, 57th and 59th President of Uruguay Leopoldo Sanguinetti, Gibraltarian poet and writer Mateo Sanguinetti (born 1992), Uruguayan rugby player Natalina Sanguinetti (born 1940), Italian fencer Robert "Bobby" Sanguinetti (born 1988), American ice hockey player
See also Palazzo Vizzani Lambertini Sanguinetti Sanguineti, an Italian surname