Heister is a German surname. Notable people with the surname include:

Beate Heister (born 1951), German billionaire Chris Heister (born 1950), Swedish politician Danny Heister (born 1971), Dutch table tennis player Leopold Philip de Heister (1716-1777), German general Lorenz Heister (1683–1758), German anatomist, surgeon and botanist Marcel Heister (born 1992), German footballer Stephen Heister, American aerospace engineer