Pleurodema tucumanum, the spotted-flanks four-eyed frog, is a species of frog in the family Leptodactylidae. It is endemic to Argentina.

Habitat This terrestrial frog is found in shrubland between above sea level. It has also been seen in agricultural habitats.

Scientists have reported the frog in protected areas: Parque Nacional Calilegua, Parque Nacional Sierra de las Quijadas, and Parque Provincial Ischigualasto.

Reproduction This frog is an explosive breeder. The male frogs sit in or near the water and call to the female frogs. The adult frogs make a foam nest for the eggs in pools of water.

Threats The IUCN classifies this frog as least concern of extinction.

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