The B-52 is an American strategic bomber aircraft.

B-52 or B52 may also refer to: The B-52s, an American new wave band The B-52's (album) B52 (New York City bus), a bus line in Brooklyn, New York B52 (chess opening), a chess opening based on the Sicilian Defence B-52 (cocktail) B-52 (hairstyle) or beehive, a hairstyle B52 (medical treatment), an intramuscular injection of three medications to treat agitation B-52 Memorial Park, a park within the Orlando International Airport, Florida Volvo B52 engine, a group of Volvo engines Nora B-52, a Serbian self-propelled howitzer HLA-B52, an HLA-B serotype Bundesstraße 52, a federal highway in Germany B52, route number for Kings Highway in Australia B-52, a coded reference to Mao Zedong in Project 571 B-52, a pennant number of the Argentinian fast transport ship