George Brooke or Brook may refer to:
George Brook (cricketer) (1888–1966), English cricketer , British zoologist George H. Brooke (1874–1938), American football player and coach George C. Brooke (1884–1934), British numismatist George Brooke (conspirator) (1568–1603), British aristocrat executed for conspiracy against James VI of Scotland and I of England George Brooke, 9th Baron Cobham (–1558), English nobleman George Brooke (MP) (), MP for Eye George J. Brooke, British biblical scholar George Mercer Brooke (1785–1851), colonel who established Fort Brooke, predecessor to Tampa, Florida George Brooke alias Cobham (), MP for Hedon and Portsmouth
See also George's Brook, Newfoundland village George Brooks (disambiguation)