Letham may refer to:

Places Letham is a common place-name element in Scotland, deriving from the Scottish Gaelic leathan, meaning "broad slope". Examples include: Letham, Angus Letham, Falkirk Letham, Fife Letham, Perth and Kinross, a suburb of Perth

People David Letham (1923–2007), Scottish football player Isabel Letham (1899–1995), Australian pioneer surfboarder Margaret Letham (born 1956), lawn and indoor bowler Robert Letham, British biblical scholar and theologian Ronnie Letham (1949–2008), Scottish actor

Other uses Letham Grange estate, Angus, Scotland Letham Grange railway station, a former station that served the estate Letham St Mark's Church, Perth

See also Lethem (disambiguation)