ESAM or Esam may refer to: ESAM (gene) Esam (given name) John Esam, performer at the International Poetry Incarnation, 1965 Mons Esam, mountain on the moon Empire State Aerosciences Museum, in Glenville, New York, United States Enfants Solidaires d'Afrique et du Monde, African anti-trafficking group Superior School of Agronomy of Mossoró (ESAM), former name of the Federal Rural University of the Semi-arid Region, Brazil