Schmidhuber is a German surname. Notable people with the surname include:
Aron Schmidhuber (born 1947), German football referee August Schmidhuber (1901–1947), German Nazi SS officer executed for war crimes Gerhard Schmidhuber (1894–1945), German general Guillermo Schmidhuber (born 1943), Mexican playwright and novelist Jürgen Schmidhuber (born 1963), German computer scientist Peter Schmidhuber (1931–2020), German politician