Methyl-MMDA-2, also known as 2-methoxy-4,5-methylenedioxy-N-methylamphetamine or as 6-methoxy-MDMA, is a psychoactive drug of the phenethylamine, amphetamine, and MDxx families. It is the N-methylated derivative of MMDA-2, and it is also an analogue of MDMA and 6-methyl-MDA.
Use and effects Methyl-MMDA-2 was first synthesized by Alexander Shulgin and was described in his book PiHKAL (Phenethylamines I Have Known and Loved). He states that it is essentially inactive at a dose of 70mg orally, and he did not test higher doses; however, Methyl-MMDA-2 is still likely to be active, perhaps in the 125 to 250 mg range. This reduction in hallucinogenic activity relative to MMDA-2 parallels that of MDA and MDMA, indicating that with phenethylamines, N-methylation substantially reduces 5-HT2A receptor affinity.
Chemistry Synthesis The chemical synthesis of methyl-MMDA-2 has been described.
See also Substituted methylenedioxyphenethylamine MMDA-2 MDMA 6-Methyl-MDA
References
External links Methyl-MMDA-2 - Isomer Design Methyl-MMDA-2 - PiHKAL - Erowid Methyl-MMDA-2 - PiHKAL - Isomer Design